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Abstract
The Potential Activity of Hydroxychavicol against Pathogenic Bacteria
Jangala Jesonbabu, Navuru Spandana and Aruna lakshmi K
Hydroxychavicol isolated from Piper betle leaves, showed inhibitory activity against gastrointestinal pathogens. It exhibited inhibitory effect on the entire gastrointestinal pathogens tested (MICs of 200-400 ?g/ml) with an MBC, which was twofold greater than the inhibitory concentration. Hydroxychavicol exhibited concentration dependent killing of Staphylococcus aureus and Escherichia coli to 4 x MIC, that the hydroxychavicol would be a useful compound for the development of antibacterial agents against gastro intestinal pathogens and has great potential for use in treatment of gastrointestinal infections.