Global Journal of Biology, Agriculture & Health Sciences

Abstract

THE EFFECT OF Sida acuta ON GLYCOGEN PROFILE OF ADULT WISTAR RAT

Kebe, E. Obeten; Gabriel Udo-Affah; Kelechi C. Uruakpa; & Anozeng O. Igiri

This study was carried out to assess the effect of ethanolic leaf extract of Sida acuta on the glycogen profile of the liver in adult Wistar rats. Thirty (30) rats weighing between 140g were assigned to three groups (A, B and C) with ten animals each. Group A served as the control while groups B and C served as the experimental groups and received 100mg/kgbw and 200mg/kgbw of the extract respectively for fourteen days. All the animals were sacrificed after fourteen days. Then animals were sacrificed, livers removed and processed for Haematoxylin and eosin (H&E) paraffin sectioning and staining method. From the results obtained, the administration of ethanolic leaf extract of Sida acuta caused no obvious structural derangement in the organ. There were no adverse effects on glycogen distribution.

Published Date: 2014-11-25;