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Journal of Bioequivalence & Bioavailability

Abstract

Suggestions for the Preliminary Definition of a Current Background Profile of Polychlorodibenzodioxin (PCDDs) and Polychlorodibenzofuran (PCDFs) Congeners in Serum Samples

Roberto Miniero, Elena De Felip and Alessandro di Domenico

The congener specific polychlorodibenzodioxins (PCDDs) and polychlorodibenzofurans (PCDFs) distribution in human body is a function of bioavailability processes needed to cross the biological membranes. The blood is the destination of major distribution of chemicals into the body. This matrix appears the most important to interpret the concentration levels determined in terms of toxicity or to link them to the interpretation of temporal and spatial trends