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Abstract
Role of Epigenetic Modification, Epigenetic Biomarkers and Dietary Supplements in Neurodegenerative Diseases
Neurodegenerative diseases are outcome of epigenetic modification and environmental factors. With the age, due to epimutation neural cell get harm and affect the cognitive function. Epigenetic biomarkers such as DNA methylation, histone modification and miRNA alter the genes functions, involved in many cellular processes. Early detection of these biomarkers help in early diagnosis of diseases. In this article we have focus on how epigenetic alteration affects the expression of genes and epigenetic biomarkers help in earlier diagnosis. We also have focus on dietary supplements which help in slowing the progression of disease.
Published Date: 2019-05-22; Received Date: 2019-03-14