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Abstract
Recent Developments in the Treatment of Intrauterine Adhesions Using Biomaterials Combined with Stem Cells
Xiao Yang, Qiuhong Chen, Ling Wei, Quanhong Shi, Shasha Wu, Yanhua Mao, Yingfeng Zhang, Changjiang Li, Congcong Sun, Peng Jiang*, Xiyue Huang*, Wenwen Zhang*
Intrauterine Adhesions (IUA) significantly impact women’s reproductive health, potentially leading to severe complications such as recurrent miscarriage and infertility. It is a significant public health issue among premenopausal women. Current treatment options are limited, and a definitive solution to prevent postoperative re-adhesions after IUA surgery has yet to be found. Although more studies demonstrate the effectiveness of stem cells in treating IUA, the drawbacks of stem cells themselves have become apparent. With the rapid development of bioengineering technology, significant developments have been made in addressing the problem of postoperative re-adhesions. Therefore, this paper primarily reviews the functions of current biomaterials combined with stem cells and their source cytokines in treating IUA. It also looks forward to research on composite multifunctional materials.
Published Date: 2024-06-25; Received Date: 2024-05-24