Tropical Medicine & Surgery

Abstract

Metastasis of Sigmoid Colon Cancer to the Breast and Uterus: A Case-Study

Andee Dzulkarnaen Zakaria, Amer Hayat Khan, Muhammad Abdul Hadi and Baharudin Ibrahim

 Introduction: Colon cancer is the second most common cancer after breast and the most common cancer among males in Peninsular Malaysia. Metastasis of colon cancer to the uterus and breast rarely occur, but still the incidence could not be ignored as it could possibly happen to anyone with the disease. Clinical Presentation and Intervention: A 32-years old Malay woman complaining of pain in the right hypochondria region radiating to the back and right shoulder. The pain was constant, with moderate intensity and relieved temporarily by analgesics (Paracetamol). She also noticed a lump in her left breast following Breast Self Examination (BSE). Patient was admitted to Hospital Universitiy Sains Malaysia (HUSM) with no signs of shortness of breath, chest pain or hemoptysis. The patient had history of sigmoid colon cancer (Duke’s B) and had undergone sigmoid colectomy two years ago and completed 25 cycles of local radiotherapy and concurrent 12 cycles of systemic chemotherapy. The ultrasound of pelvic region revealed metastasis to pelvic organ. Conclusion: Surgery is the most common treatment for colorectal cancer and may be curative for localized cancers. Radiotherapy and chemotherapy be used as an adjunct treatment after surgery to increase disease free survival and overall survival but recurrence may still occur.