Abstract

Low-Level Laser Therapy: As a New Approach to Modulate Oxidative Stress in Diabetes Mellitus and its Complications

Mohammad Reza Ashoori, Afsaneh Seyed Mikaeili, Hossein Mirmiranpour and Saeedeh Abdolahpour*

As a chronic metabolic disease, Diabetes Mellitus (DM) can be strongly associated with a combination of heredity, environmental factors and lifestyle, demanding life-through control and management. This condition can also have irreparable consequences such as cardiovascular abnormalities, brain damage, nephropathy, Diabetic Peripheral Neuropathy (DPN) and diabetic wounds and even death. In today’s modern world, many individuals are at most risk of DM and its consequences. Accordingly, insulin injection and medications are being used to control type 1 and type 2 DM, respectively. However, DM can result in the production of free radicals and oxidative stress, as one of the most important consequences. In this respect, Low-Level Laser Therapy (LLLT) has been introduced as a novel form of phototherapy, which is being practiced as a non-invasive and safe method. Nowadays, oxidative stress reduction and cell proliferation in low-level laser exposed tissues have been further taken into consideration. Therefore, LLLT has been utilized as a complementary method for treatment of some DM consequences, such as skin wounds.

Published Date: 2024-09-13; Received Date: 2021-02-22