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Abstract
Importance of Different Hpv Genotypes in the Development of Cervical Cancer
González Bosquet E and Mazarico E
Fifteen human papillomavirus genotypes are implicated in the appearance of precancerous and cancerous lesions in uterine cervix. The two vaccines against cervical cancer currently available on the market contain only the two high-risk HPV genotypes (16 and 18) identified as the most prevalent. Other high-risk genotypes like papilloma virus 31, 51, 53 and 58 were isolated more frequently than HPV 18 in our study and in a review of the literature, in women with precancerous and cancerous lesions in uterine cervix. These results could explain the loss effectiveness of the vaccine in certain circumstances and support the need of continuing cervical cancer screening per current guidelines.