Journal of Nanomedicine & Nanotechnology

Abstract

Green synthesis of silver nanoparticle using four ethno medicinal plant Kalanchoe pinnata, Artocarpus Heterophyllus, Vitex negundo and Millettia pinnata of Jharkhand

Ladly Rani*, R Verma, Shweta Kashyap, Rahul Kumar Mandal, Abhijeet Hembrom, S K Jha and Kunul Kandir

In the present study, a plant-mediated green method of synthesizing AgNPs was successfully performed by employing the leaf extracts of ethnomedicinal plants used traditionally by ethnic people for curing various diseases Artocarpus heterophyllus and Kalanchoe pinnata (fresh), Vitex negundo and Millettipinnata as a source of reducing an

Stabilizin agents is reporte. Nanoparticles are particles having diameters below 100 nm. The nanoparticles formed were characterized using UV-Vis spectrophotometer, scanning FT-IR. A Surface Plasmon Resonance (SPR) peak was observed at 450 nm. UV-V is analysis. The FT-IR analysis spectra peak were observed at Artocarpus heterophyllus (1532.40 cm^-1, 1373.50 cm-1, 1221.40 cm-1, 961.31 cm^-1 and 545.35 cm-1) Kalanchoe pinnata (1738.60 cm, 1549.30 cm, 1370.10 cm, 1218.00 cm, 1005.00 cm) Vitex negundo (2,326 cm, 2921.7 cm, 1731.8 cm, 1626 cm, 1525.8 cm, 1366.8 cm, 1224.8 cm, 987.89 cm, 525.63 cm) and Millettia pinnata (2911.5 cm^-1 , 1623.7 cm-1, 1529 cm-1, 1373.5 cm-1, 1211.3 cm-1 and 947.6 cm-1), which corresponds to the presence of capping agents such as primary and secondary amines, hydroxyl compounds, flavonoids, alcoholic and phenolic compounds the stability of the synthesized nanoparticles. The AgNPs synthesized in the present study displayed antibacterial activity against E. coli which suggested that they may play a role in new drug development The AgNPs synthesized in the present study displayed significant antibacterial activity against E. coli in comparision to antibiotics and crude extract.

Published Date: 2023-07-31; Received Date: 2023-07-03