Biology and Medicine

Abstract

Epidemiological Analysis of HIV and HPgV Co-infection in Brazilian Population

Evônio de Barros Campelo Júnior, Ana Maria Passos de Castilho, Viviane Martha Santos de Morais, Georgea Gertrudes de Oliveira Mendes Cahú, Gabriel Galindo Cunha, Vitoria Maria de Araújo Oliveira, Ricardo de Arraes Alencar Ximenes and Maria Rosângela Cunha Duarte Coêlho*

Aim: This study aimed to determine the prevalence of Human Pegivirus 1(HPgV) infection among People Living with HIV (PLWHIV) in Northeast Brazil and identify associated risk factors, given the potential impact of HPgV on HIV (Human Immunodeficiency Virus) disease progression

Materials and Methods: We conducted a cross-sectional analysis of 249 People Living with HIV (PLWHIV) receiving care at a tertiary hospital in Northeast Brazil. Bivariate and multivariate logistic regression models were used to assess the association between sociodemographic characteristics, risk behaviors, healthcare access and HPgV infection.

Results: The prevalence of HPgV infection among the study population was 23.3%. Inhaled drug use emerged as a significant risk factor for HPgV infection in the multivariate analysis.

Conclusion: A concerning prevalence of HPgV infection exists among PLWHIV in Northeast Brazil. The identification of inhaled drug use as a risk factor suggests potential transmission routes beyond traditional modes. These findings highlight the need for targeted public health interventions and harm reduction strategies to address this significant public health concern.

Published Date: 2024-10-30; Received Date: 2024-08-28