Modern Chemistry & Applications

Abstract

Effective Treatment of an Unhealed Incision of a Diabetic Patient with Recombinant Human Epidermal Growth Factor

WKR Wong

A facile protocol, which involves topical application of recombinant human Epidermal Growth Factor (rhEGF), was previously developed by our group and shown to be effective in treating diabetic foot ulcers, when working in conjunction with debridement surgery. In this communication, using the same approach of rhEGF application, despite the absence of debridement, our findings demonstrated that the protocol worked equally well on a hard-to-heal wound, which remained unhealed subsequent to surgical removal of the great saphenous vein from the left thigh of a diabetic patient. After treatment with rhEGF for 10 d, the wound was shown to heal readily and finally achieved complete healing. The success of rhEGF in the healing process is concluded to be attributable to both the fine quality and sufficient dosage of rhEGF.