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Abstract
Development and Application of Cancer Stem Cell-Targeted Vaccine in Cancer Immunotherapy
Ming Lin, Alfred E. Chang, Max Wicha, Qiao Li and Shiang Huang
Accumulating evidence shows that tumours contain a distinct subpopulation of cancer stem cells (CSCs) which are capable of selfrenewal, differentiation, and tumour-initiation . Previous studies have demonstrated that cancer stem cells are relatively resistant to chemo-and radio-therapies