Journal of Stem Cell Research & Therapy

Abstract

Complex Treatment of Erectile Dysfunction with Vascular Factor Deficit by Use of Pluripotent Fetal Stem Cells

Klunnyk MO, Matiyashchuk IG, Sych NS, Sinelnyk AA, Miroshnykov IO and Sorochynska KI

Objective: To study the effect of combined therapy including fetal stem cells (FSCs) on different components of erections.
Material and methods: During a period of 2014-2015 years 19 patients with mixed type erectile dysfunction and mandatory vascular factor documented by pharmacodopplerography were under study in Cell Therapy Center EmCell. The program of examination for patients in the Main Group (MG) and Control Group (CG) included the scales of International Index of Erectile Function (IIEF) questionnaire, urine analysis, tests for total and free testosterone, Sex Hormone Binding Globulin (SHBG), Free Androgen Index (FAI), blood glucose and glycosylated Hemoglobin (HbA1c) testing, lipidogram findings, pharmacodopplerography of cavernous vessels, study of cortical and diencephalon components of erection by use of clinical methods and the questionnaires of State-Trait Anxiety Inventory – (STAI) and Beck Depression Inventory (BDI).
Conclusion: combined use of vardenafil and cryopreserved suspensions containing pluripotent FSCs extracted from fetal liver, brain and placenta promotes favorable effect on all components of erections.