Journal of Bacteriology & Parasitology

Abstract

Comparative Investigation of Commercially Available Anti-Bacterial Creams for their Efficacy Against Different Bacterial Strains

Parthika Patel*, Isha Patel, Sayli Kachare and Priyanka Maurya

Introduction: Antibacterial creams play a vital role in the treatment of bacterial skin infections. With numerous products available, these creams differ significantly in concentration, price, activity levels, active ingredients and excipients. The choice of cream is critical for effective treatment and depends on the specific bacterial strains involved. Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), Bacillus subtilis (B. subtilis) and Proteus vulgaris (P. vulgaris) are four bacterial strains commonly associated with human illnesses and skin disorders. This study aims to evaluate the antibacterial efficacy and economic viability of four popular commercial antibacterial creams containing either Gentamicin sulfate, Framycetin sulfate, or a combination of Silver sulfadiazine, Miconazole nitrate, Neomycin sulfate and Chlorhexidine gluconate. The objective is to identify the most effective and economical option among these creams.

Materials and Methods: This study was designed to evaluate the antibacterial efficacy and economic viability of four popular commercial antibacterial creams against four bacterial strains commonly responsible for human skin infections. The study employed a laboratory based experimental design using the disk diffusion method to assess the antibacterial activity of each cream.

Results and Conclusion: Gentamicin sulfate emerges as the top-performing antibacterial cream in this study, exhibiting the widest zones of inhibition against key bacterial strains. Its potent antibacterial efficacy is complemented by favorable physical properties such as low pH, high spreadability and low viscosity. These findings position Gentamicin sulfate as a preferred choice for effectively treating bacterial skin infections.

Published Date: 2024-08-21; Received Date: 2024-07-19