Advances in Pharmacoepidemiology and Drug Safety

Abstract

Chemotherapy for Primary Adenocarcinoma of the Urinary Bladder: Case Report

Xu W, Yu B, Xu T, Xu Z, Cai H and Zou Q

A 71-year-old man was admitted to the hospital because of frequent micturition, urgency of urination and vesical tenesmus for one month. For the recent one week, the symptoms above aggravated gradually, accompanied with indisposition and distention of lower abdomen. Cystoscopic examination revealed that the blister lesions which were transparent protruded into the hanging and lateral wall of the bladder. The pathological biopsy showed it was adenocarcinomas of the urinary bladder. The patient was treated with GC plus S-1 chemotherapy with a regular follow-up. The progress of the disease was evaluated according to the standard of curative effect of RECIST. Traditionally, GC is considered as first-line chemotherapy for urothilial cell carcinoma. In this study, we researched the efficacy of GC plus S-1 combination chemotherapy in the study.