Journal of Nanomedicine & Nanotechnology

Abstract

Biosynthesis of Nanoparticles and their Antibacterial Properties

Abhishek Tiwari*

Diatoms are a rich source of metabolites with numerous uses, and because of their silica frustules, diatoms' silver nanoparticle (AgNP) has tremendous therapeutic potential for use against pathogenic microorganisms. In the current investigation, AgNP was synthesised using Chaetoceros sp., Skeletonema sp., and Thalassiosira sp. According to DLS data, the average size of the synthesised AgNP particles was 149.03 3.0 nm, 186.73 4.9 nm, and 239.46 44.3 nm, but SEM data showed 148.3 46.8 nm, 238.0 60.9 nm, and 359.8 92.33 nm, respectively. AgNP exhibiting a prominent peak of Ag+ ion within the spectra is strongly supported by EDX analysis. High negative zeta potential values suggest significant stabilisation even three months later. Aeromonas sp., Escherichia coli, and other bacteria were used to assess the biosynthesized AgNP's antibacterial activity. Broadspectrum antibacterial action is seen in Staphylococcus aureus, Streptococcus pneumonia, and Bacillus subtilis. Due to its low toxicity and biodegradable nature, this work stimulates the synthesis of diatom-based AgNP for a number of applications.

Published Date: 2022-11-30; Received Date: 2022-11-01