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Abstract
Bioinformatics for Viral Metagenomics
Davit Bzhalava and Joakim Dillner
Detection of the presence of known and unknown viruses in biospecimens is today routinely performed using viral metagenomics. Because the sequencing speed and cost per base is rapidly declining with new next generation sequencing technologies, such as HiSeq (Illumina), 454 GS FLX (Roche), SOLiD (ABI) and Ion Torrent Proton (Life Technologies), the bioinformatics analysis is today a most important and increasingly demanding part of viral metagenomics analysis. In this review, we highlight some of the major challenges and the most commonly adapted bioinformatics tools for viral metagenomics.