Journal of Microbial & Biochemical Technology

Abstract

Anti-Tumor, Antioxidant and Antimicrobial and the Phenolic Constituents of Clove Flower Buds (Syzygium aromaticum)

Abd El Azim M H M, Amani M D El-Mesallamy, El-Gerby M and Awad A

Eleven phenolic compounds were identified from the methanolic extract of Cloves flowers buds (Syzygium aromaticum L.) by chromatographic methods. Efficiency of the methanolic extract of licorice roots as anticancer agent for breast, colon and liver was tested. The results showed that the IC50 were (31 μg/mL for anti-colon cancer, 29.7 μg/ml for anti-breast cancer and 18.7 μg /ml for anti-hepatic cancer). This extract showed strong antioxidant activity against 2, 2-diphenyl-1-picrylhydrazyl (DPPH.) as compared with vitamin C. Antimicrobial activity of the methanol extract of licorice roots was studied against three bacterial and four fungal strains at concentration 0.1 ml and 0.3 ml (10 mg/1 ml)). The extract showed strong inhibitory effect for most species at concentration 0.3 ml (10 mg/ ml).