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Abstract
Analysis of serum immunoglobulins using Fourier transform infrared spectral measurements
G Sankari, E Krishnamoorthy, S Jayakumaran, S Gunasekaran, V Vishnu Priya, Shyama Subramaniam, S Subramaniam, Surapaneni Krishna Mohan
Fourier Transform Infra Red (FTIR) Spectroscopy is a non-invasive, reagent free diagnostic tool in the analysis of biological fluids. The results can be best employed in the qualitative and quantitative investigation of biological fluids. Multiple myeloma is a disorder in which malignant plasma cells accumulate in bone marrow and produce excess immunoglobulin that leads to many complications. The present work is attempted in the study of normal and three different myeloma affected blood samples IgA, IgG and IgM using FTIR Spectroscopy. Internal Standard method is adopted in characterizing the samples quantitatively